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| Corleta,H.; Capp,E.; Strowitzki,T.. |
| Endometrium is one of the fastest growing human tissues. Sex hormones, estrogen and progesterone, in interaction with several growth factors, control its growth and differentiation. Insulin-like growth factor 1 (IGF-1) interacts with cell surface receptors and also with specific soluble binding proteins. IGF-binding proteins (IGF-BP) have been shown to modulate IGF-1 action. Of six known isoforms, IGF-BP-1 has been characterized as a marker produced by endometrial stromal cells in the late secretory phase and in the decidua. In the current study, IGF-1-BP concentration and affinity in the proliferative and secretory phase of the menstrual cycle were measured. Endometrial samples were from patients of reproductive age with regular menstrual cycles and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: IGF-1; Binding protein; Endometrium. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001100019 |
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| Devi,Subramaniam Mohana; Park,Jae Won; Kim,In Ho. |
| ABSTRACTThe objective of the present study is to evaluate the effects of plant extracts on growth performance, nutrient digestibility, and immune blood characteristics in growing pigs. A total of 80 [(Landrace × Yorkshire) × Duroc] pigs with an initial body weight (BW) of 27.31±2.15 kg were used in a 6-wk experiment. Pigs were allotted to one of four treatments (1 - Control (CON) (basal diet); 2 - PE1 (CON + 0.05% plant extracts); 3 - PE2 (CON + 0.10% plant extracts); and 4 - PE3 (CON + 0.15% plant extracts)) in a randomized complete block design according to sex and initial BW. The PE1 and PE2 treatments provided a greater average daily gain than the CON treatment. From weeks 0 to 6 the pigs fed diets PE2 and PE3 showed greater apparent total tract... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: IGF-1; Plant extract. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982015001000355 |
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| Almeida,M.V.D.; Castro,D.S.; Rial,L.C.; Lustosa,J.P.; Bicalho,A.L.F.; Ortega,H.H.; Salvetti,N.R.; Caliari,M.V.; Vieira,F.G.; Valle,G.R.. |
| Com o objetivo de verificar a presença de VEGF e IGF-1 nos ovários de cadelas, foram realizadas análises imuno-histoquímicas do estroma cortical; teca e granulosa de folículos secundários, terciários e terciários pré-ovulatórios luteinizados; e ovócitos de folículos primários, secundários e terciários de ovários de cinco cadelas em anestro (Anest) e cinco em estro (Est). A identificação das fases do ciclo estral foi realizada por citologia vaginal associada a dosagem plasmática de progesterona. Os ovários foram submetidos a tratamento imuno-histoquímico para identificação de VEGF (anticorpo primário PU 360-UP, Biogenex, USA; diluição 1:30) e IGF-1 (anticorpo primário PabCa, Gro-Pep, Austrália; diluição 1:100). Determinou-se um índice de imunomarcação (IM),... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cadela; Ovário; Ovócito; VEGF; IGF-1. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352015000200334 |
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| COSTA-SILVA,DANYLO R.; BARROS-OLIVEIRA,MARIA DA CONCEIÇÃO; BORGES,RAFAEL S.; TAVARES,CLÉCITON B.; BORGES,UMBELINA S.; ALVES-RIBEIRO,FRANCISCO A.; SILVA,VLADIMIR C.; SILVA,BENEDITO B. DA. |
| ABSTRACT Insulin-like Growth Factor-1 (IGF-1) gene polymorphism has been associated with an increased risk for breast cancer. IGF-1 is a key regulator of proliferation, cell differentiation and apoptosis. It has important mitogenic and anti-apoptotic activities in normal cells and in breast cancer cells, acting synergistically with estrogen to increase neoplastic cell proliferation. This review aims to present the recent finds of IGF-1 gene polymorphism and its relationship with the risk of breast cancer through following the polymorphic dinucleotide repeat cytosine-adenine (CA) and single nucleotide polymorphisms (SNPs) by searching in the PubMed database publications focused studies published from 2010 to 2015 related to IGF-1 gene polymorphism and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Breast cancer; Risk factors; IGF-1; IGF-1 gene polymorphism. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000602349 |
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| Franzoni,Ana Paula Saldanha; Gloria,Joana Ribeiro da; Costa,Anna Luiza Belli de Souza Alves; Martins,Ronaldo Alves; Amaral,Thiago Fernandes; Azevedo,Rafael Alves de; Campos,Ernane Ferreira; Coelho,Sandra Gesteira. |
| Abstract: The objective of this work was to describe the effect of genetic composition on body condition score (BCS), on total lactation production, and on metabolic and hormone profiles of Holstein x Gyr cows under the same pre- and postpartum management conditions. The genetic groups ½ (n=8), – (n=10), and ≥⅞ (n=10) Holstein x Gyr (HG) were evaluated within the same farm, and all of them showed typical lactation curves. The time required to reach peak production did not differ between groups. The groups also did not differ as to time to reach the lowest BCS after calving or to recover BCS after calving, nor as to their BCS values in the week of first ovulation, number of weeks required for first ovulation, and service period. However, ½ HG cows had... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bos indicus; Bos taurus; GH; IGF-1; Lactation curve; Transition period. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2018000300371 |
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| Gottschall,C.; Glanzner,W.G.; Almeida,M.R.; Canellas,L.C.; Martins,C.T.D.C.; Weimer,T.A.; Bittencourt,H.R.; Mattos,R.C.; Gregory,R.M.. |
| O objetivo deste estudo foi buscar associação entre a taxa de prenhez após inseminação e natalidade com marcadores moleculares ligados aos genes do receptor para IGF-1, LHβ, Leptina e receptores do FSH e LH. Utilizaram-se 249 vacas adultas Aberdeen Angus, das quais 199 foram submetidas a protocolos distintos para a IATF, seguida pelo repasse com touros, e 50 vacas formaram o grupo controle representado pelo acasalamento com touros. Foram avaliados o escore de condição corporal (ECC) e o escore de condição ovariana (ECO) ao início da estação reprodutiva. O ECC influenciou a taxa de natalidade, respectivamente de 55,6%, 75,8% e 82,4% (P<0,05) para os animais com ECC menor que 2,5, entre 2,5 a 2,9, e maior ou igual a 3,0, por ocasião da estação... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bovinos (Bos taurus); Escore de condição corporal; IGF-1; Taxa de natalidade. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000600004 |
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| Tian,Y.G.; Yue,M.; Gu,Y.; Gu,W.W.; Wang,Y.J.. |
| Tibetan (TB) and Bama (BM) miniature pigs are two popular pig breeds that are used as experimental animals in China due to their small body size. Here, we analyzed single-nucleotide polymorphisms (SNPs) in gene fragments that are closely related to growth traits [growth hormone (GH), growth hormone receptor (GHR), and insulin-like growth factor (IGF)-1)] in these pig breeds and a large white (LW) control pig breed. On the basis of the analysis of 100 BMs, 108 TBs, and 50 LWs, the polymorphic distribution levels of GH, GHR, and IGF-1 were significantly different among these three pig breeds. According to correlation analyses between SNPs and five growth traits - body weight (BW), body length (BL), withers height (WH), chest circumference (CC), and abdomen... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Minipigs; SNP; GH; GHR; IGF-1. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000900753 |
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| Al-Zghoul,MB; Al-Natour,MQ; Dalab,AS; Alturki,OI; Althnaian,T; Al-ramadan,SY; Hannon,KM; El-Bahr,SM. |
| ABSTRACT Thermal manipulation (TM) during broiler chicken embryogenesis has been shown to promote muscle development and growth. However, the molecular bases of promoting broiler muscle development and growth are not fully understood. The aim of this study was to investigate the molecular bases of muscle growth and development in broiler chickens subjected to TM. This included the investigating of the changes in mRNA expression levels of muscle marker genes, namely MyoD, myogenin, paired box transcription factor (Pax7) and proliferating cell nuclear antigen (PCNA), and muscle growth factors namely insulin-like growth factor 1 (IGF-1), myostatin and growth hormone (GH) during embryogenesis and on posthatch days 10 and 28. Fertile Cobb eggs (n=1500) were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Embryogenesis; IGF-1; MyoD; Myostatin; Thermal manipulation. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2016000400607 |
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